EPA and inflammatory processes

One of the most noteworthy areas of EPA is its beneficial effects in inflammatory processes. DHA has also interesting features in the field of inflammation, although the mode of action is different from EPA. Specifically, numerous studies have shown the benefits of EPA to relieve inflammation in autoimmune processes, especially in musculoskeletal tissues, as well as in respiratory or skin problems.

  • Gillies PG et al., (2012) Regulation of inflammatry and lipid metabolism genes by eicosapentaenoic acid rich oil. Journal of Lipid Research 53: 1679-1689.
  • Mickleborough TD et al., (2008) Eicosapentaenoic acid is more effective than Docosahexaenoic acid in inhibiting proinflammatory mediators production and transcription from LPS-induced human asthmatic macrophage cells. Clinical Nutrition 28 (1): 71-77.
  • Wann AKT et al. (2010) Eicosapentaenoic acid and docosahexaenoic acid reduce interleukin 1-mediated cartilage degradation. Arthritis Research & Therapy 12: R207

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